Colgate Total® Active Prevention+, er optimeret til maksimal ydeevne via 3 centrale fordele:
Tin- og fluorid-ioner har komplementære egenskaber for at forebygge mange almindelige orale sundhedsproblemer6
Tin-ioner er generelt ustabile og oxiderer let ved kontakt med luft, vand og varme8
Fosfat beskytter komplekse Sn2+ ioner mod oxidation
Den formulering af Colgate Total® er udviklet til at forbedre stabiliteten af bioaktive tin-ioner
Nitrat-ioner bidrager til at forhindre nedbrydning af det bioaktive Sn2+
Sn2+ = stannous cation. *US Patented. †Superior performance vs non-antibacterial fluoride toothpaste. §With 2x daily brushing and 4 weeks of continued use. #With twice-daily use after 4 weeks. **Consumer Home Use Test (HUT) in 2023 with 450 consumers – US, BZ, UK. ^Soluble stannous measured via aqueous simple solutions of the ingredients after 2 weeks’ accelerated ageing at 60°C. ‡Vs non-antibacterial fluoride toothpaste after 3 months of continued use. ^^Vs non-antibacterial fluoride toothpaste with 6 months of continued use. ††On former and current formulas of Colgate Total®globally.
References: 1. Rösing CK. Advanced Oral Health Protection: A Multifunctional Dentifrice Designed to Prevent Oral Diseases and Conditions. Compend Contin Educ Dent. 2024;45 (Spec Iss):2-5. 2. Ledder RG, et al. Visualization and Quantification of the Oral Hygiene Effects of Brushing, Dentifrice Use, and Brush Wear Using a Tooth Brushing Simulator. Front Public Health. 2019;7:9122. 3. Paqué PN, et al. Microbial approaches for the assessment of toothpaste efficacy against oral species: A method comparison. Microbiology Open. 2022;11(2):e1271. 4. Gittins A, et al. Efficacy of a Stannous Fluoride Toothpaste Stabilized With K+ and Polyphosphates (SNAP) on Immediate Tooth Sensitivity Relief. J Dent Res. 2022;101 (Spec Iss A):0512. 5. Hu D, et al. Stannous Fluoride vs Regular Fluoride Dentifrice in Plaque and Gingivitis Reduction. J Dent Res. 2022;101(Spec Iss A):0514. 6. Kruse AB, et al. Long-Term Use of Oral Hygiene Products Containing Stannous and Fluoride Ions: Effect on Viable Salivary Bacteria. Antibiotics (Basel). 2021;10(5):481. 7. Clark-Perry D, Levin L. Comparison of new formulas of stannous fluoride toothpastes with other commercially available fluoridated toothpastes: A systematic review and meta-analysis of randomised controlled trials. Int Dent J. 2020;70(6):418-26. 8. Dorn RW, et al. Structural characterization of tin in toothpaste by dynamic nuclear polarization enhanced 119Sn solid-state NMR spectroscopy. Nat Commun. 2023;14:7423. 9. Seriwatanachai D, et al. Clinical Results Of 4wk Antibacterial Study For Stannous Fluoride Toothpaste. J Dent Res. 2024;103(Spec Iss A):1082. 10. Chakraborty B, Seriwatanachai D, Triratana T, et al. Antibacterial Effects of a Novel Stannous Fluoride Toothpaste Stabilized With Nitrate and Phosphates (SNaP): In Vitro Study and Randomized Controlled Trial. Compend Contin Educ Dent. 2024;45 (Spec Iss):12-20. 11. Stellitano M, et al. Effect of a Stannous Fluoride Toothpaste on Supragingival Calculus Formation, submitted for 2025 AADOCR presentation.